PUBLICATIONS ANTÉRIEURES
2004
Chen Z, Gaudreau R, Le Gouill C, Rola-Pleszczynski M, Stankova J. Agonist-induced internalization of leukotriene B(4) receptor 1 requires G-protein-coupled receptor kinase 2 but not arrestins, Mol Pharmacol. 2004 Sep;66(3):377-86.

Dupre DJ, Le Gouill C, Gingras D, Rola-Pleszczynski M, Stankova J. Inverse agonist activity of selected ligands of the cysteinyl-leukotriene receptor 1, J Pharmacol Exp Ther. 2004 Apr;309(1):102.

Dupre DJ, Rola-Pleszczynski M, Stankova J. Inverse agonism: more than reverting constitutively active receptor signaling, Biochem Cell Biol. 2004 Dec;82(6):676-680.

Fülöp T, Larbi A, Douziech N, Fortin C, Guérard KP, Lesur O, Khalil A, Dupuis G. Signal transduction and functional changes in neutrophils with aging, Aging Cell 3, 217-226 (2004).

Gaudreau R, Beaulieu ME, Chen Z, Le Gouill C, Lavigne P, Stankova J, Rola-Pleszczynski M. Structural determinants regulating expression of the high affinity leukotriene B4 receptor: involvement of dileucine motifs and alpha-helix VIII, J Biol Chem. 2004 Mar 12;279(11):10338-45.

Ilangumaran S, Ramanathan S, Rottapel R. Regulation of the immune system by SOCS family adaptor proteins, Semin Immunol. 2004 Dec;16(6):351-65.

Larbi A, Douziech N, Dupuis G, Khalil A, Pelletier H, Guérard KP, Fülöp T Jr. Age-associated alterations in the recruitment of signal-transduction proteins to lipid rafts in human T lymphocytes , Journal of Leukocyte Biology 2004. 75, 373-381.

Larbi A, Douziech N, Khalil A, Dupuis G, Gherairi S, Guérard KP, Fülöp T Jr. Effects of methyl-beta-cyclodextrin on T lymphocytes lipid rafts with aging, Experimental Gerontology 2004. 39, 551-558.

Larbi A, Dupuis G, Douziech N, Khalil A, Fulop T Jr. Low-grade inflammation with aging has consequences for T-lymphocyte signaling, Ann N Y Acad Sci. 2004 Dec;1030:125-33.

Lemiere C, Pelissier S, Tremblay C, Chaboillez S, Thivierge M, Stankova J, Rola-Pleszczynski M.. Leukotrienes and isocyanate-induced asthma: a pilot study, Clin Exp Allergy. 2004 Nov;34(11):1684-9.

Rochdi MD, Laroche G, Dupré E, Giguère P, Lebel A, Watier V, Hamelin E, Lépine MC, Dupuis G, Parent JL . Nm23-H2 interacts with a G protein-coupled receptor to regulate its endocytosis through an Rac1-dependent mechanism, Journal of Biological Chemistry 2004. 279, 18981-18989.

2003
Barbar E, Rola-Pleszczynski M, Payet MD, Dupuis G. Protein kinase C inhibits the transplasma membrane influx of Ca2+ triggered by 4-aminopyridine in Jurkat T lymphocytes, Biochim Biophys Acta, Jul 23;1622(2):89-98, 203.

Chen Z, Rola-Pleszczynski M, Stankova J. Activation of ERK1/2 by platelet-activating factor receptor is independent of receptor internalisation and G-protein activation, Cell Signal, Sep;15(9):843-50, 2003.

Dupré DJ, Chen Z, Le Gouill C, Thériault C, Parent JL, Rola-Pleszczynski M and Stankova J. Trafficking, Ubiquitination and Down-regulation of the human Platelet-Activating Factor Receptor, J Biol Chem, 278:48228-48235, 2003.

Espinosa K, Bosse Y, Stankova J, Rola-Pleszczynski M. CysLT1 receptor upregulation by TGF-beta and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4, J Allergy Clin Immunol, May;111(5):1032-40, 2003.

Fulop T Jr, Larbi A, Dupuis G, Pawelec G. Ageing, autoimmunity and arthritis: Perturbations of TCR signal transduction pathways with ageing - a biochemical paradigm for the ageing immune system, Arthritis Res Ther, ;5(6):290-302, 2003.

Holleran BJ, Barbar E, Payet MD, Dupuis G. Differential recruitment of alpha2beta1 and alpha4beta1 integrins to lipid rafts in Jurkat T lymphocytes exposed to collagen type IV and fibronectin., J Leukoc Biol, Feb;73(2):243-52, 2003.

Lehoux G, Le Gouill C, Stankova J, Rola-Pleszczynski M. Upregulation of expression of the chemokine receptor CCR5 by hydrogen peroxide in human monocytes, Mediators Inflamm, Feb;12(1):29-35, 2003.

Lukashova V, Chen Z, Duhe RJ, Rola-Pleszczynski M, Stankova J. Janus kinase 2 activation by the platelet-activating factor receptor (PAFR): roles of Tyk2 and PAFR C terminus, J Immunol, Oct 1;171(7):3794-800, 2003.

Marrache AM, Gobeil F Jr, Bernier SG, Stankova J, Rola-Pleszczynski M, Choufani S, Bkaily G, Bourdeau A, Sirois MG, Vazquez-Tello A, Fan L, Joyal JS, Filep JG, Varma DR, Ribeiro-Da-silva A, Chemtob S. Platelet activating factor receptors, Adv Exp Med Biol, 525:161-4, 2003.

McMahon S, Laprise MH, Dubois CM. Alternative pathway for the role of furin in tumor cell invasion process. Enhanced MMP-2 levels through bioactive TGFbeta, Exp Cell Res, Dec 10;291(2):326-39, 2003.

Perron A, Chen ZG, Gingras D, Dupre DJ, Stankova J, Rola-Pleszczynski M. Agonist-independent desensitization and internalization of the human platelet-activating factor receptor by coumermycin-gyrase B-induced dimerization, J Biol Chem, Jul 25;278(30):27956-65, 2003.

Posthaus H, Dubois CM, Muller E. Novel insights into cadherin processing by subtilisin-like convertases, FEBS Lett, Feb 11;536(1-3):203-8, 2003.

Serra P, Amrani A, Yamanouchi J, Han B, Thiessen S, Utsugi T, Verdaguer J, Santamaria P. CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells, Immunity, Dec;19(6):877-89, 2003.

Srour N, Lebel A, McMahon S, Fournier I, Fugere M, Day R, Dubois CM. TACE/ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity, FEBS Lett., Nov 20;554(3):275-83, 2003.

Yamanouchi J, Verdaguer J, Han B, Amrani A, Serra P, Santamaria P. Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens, J Immunol, Dec 15;171(12):6900-9, 2003.


2002
Amrani A, Serra P, Yamanouch J, Thiessen S, Verdaguer J and Pere Santamaria. CD154-dependent priming of diabetogenic CD4+ T-cells dissociated from activation of antigen-presenting cells, Immunity, 16, 719-732, 2002.

Chen Z, Dupré DJ, Le Gouill C, Rola-Pleszczynski M, Stankova J . Agonist-induced internalization of the platelet-activating factor receptor is dependent on arrestins but independent of G-protein activation. Role of the C-terminus and the D/NPXXY motif, J. Biol. Chem, 277:7356-7362, 2002.

Coulombe M, Battistini B, Stankova J, Pouliot P, Bissonnette EY. Endothelins Regulate Mediator Production in Rat Tissue-Cultured Mucosal Mast Cells. Upregulation of Th1 and inhibition of Th2 cytokines, J. Leuk. Biol, 71:829-836, 2002.

Douziech N, Seres I, Larbi A, Szikszay E, Roy PM, Arcand M, Dupuis G et Filep T Jr. Modulation of human lymphocyte proliferative response with aging, Exp. Gerontol, 37, 369-387, 2002.

Gaudreau R, Le Gouill C, Venne MH, Stankova J and Rola-Pleszczynski M. Threonine 308 within a putative CK2 site of the cytoplasmic tail of leukotriene B4 receptor (BLT1) is crucial for ligand-induced, GRK6-mediated desensitization, J. Biol. Chem, 277(35):31567-76, 2002.

Hickey MJ, Sihota E, Amrani A, Santamaria P, Zbytnuik LD, Ng ES, Ho W, Sharkey KA, Kubes P. Inducible nitric oxide synthase (iNOS) in endotoxemia: chimeric mice reveal different cellular sources in various tissues, FASEB J, 16:1141-3, 2002.

Laprise M-H, Grondin F Cayer, P McDonald PP, Dubois CM. Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: Involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates, Blood, 100:3578-3587, 2002.

Marrache A M, Gobeil F jr, Bernier SG, Stankova J, Rola-Pleszczynski M, Choufani S, Bkaily G, Bourdeau A, Sirois MG, Fan L, Filep J, Varma D R, Ribeiro-da-Silva A, Chemtob S. Nuclear Localization of Functional Receptors for Platelet Activating Factor, J Immunol, 169:6474-81, 2002.

Serra P, Amrani A, Han B, Yamanouchi J, Thiessen SJ, Santamaria P. RAG-dependent peripheral T cell receptor diversification in CD8+ T lymphocytes, Proc Natl Acad Sci, 99:15566-71, 2002.

Stankova J, Turcotte S, Harris J, Rola-Pleszczynski M . Modulation of leukotriene B4 receptor-1 expression by dexamethasone: Potential mechanism for enhanced neutrophil survival, J. Immunol, 168:3570-3576, 2002.

Filep T Jr, Douziech N, Larbi A et Dupuis G . The role of lipid rafts in T lymphocyte signal transduction with aging, Ann. NY Acad. Sci, 973, 302-304, 2002.

Thiessen S, Serra P, Amrani A, Verdaguer J, Santamaria P. T-Cell Tolerance by Dendritic Cells and Macrophages as a Mechanism for the Major Histocompatibility Complex-Linked Resistance to Autoimmune Diabetes, Diabetes, 51:325-338, 2002.